Friday, March 22, 2019

Essay --

1) Identify synthesis methods that atomic number 18 engrossd to make the nanomaterials for your application (1 separate synthesis method per squad member). Briefly describe how from each one synthesis method works, and classify each as top-down or bottom-up. For drug delivery, numerous processes exist that make up nanotechnology. A very common procedure for promoting drug delivery, is through the use of nanoparticles. This allows for a controlled drug release. By using nanoparticle technology, drugs evict be set inside a vehicle which helps decrease the rate at which express drug will metabolize. Targeted drug delivery is also possible, due to item nanoparticles releasing the drug once it reaches its destination. This reduces total drugs needed as healthful as the side effects, due to a more efficient transporting mechanism. weighty the costs is another benefit as well. Anything smaller than 100 nm is considered a nanoparticle. Four common nanoparticles used are silica ( SiO2), specious (Au), magnetite (Fe3O4), and quantum dots. Silica nanoparticles are very inert so they mountain be used with very reactive drugs. Due to the nature of the shape, size, and emplacement of these nanoparticles, they can bypass the RES (reticuloendothelial system). The drugs will then not be recognized as foreign and can thus be delivered to their indicate with minimal issue. Silica nanoparticles can also be mesoporous, which has pore sizes of 2-50 nm.2They can have a unique arrangement with a core crush architecture which allows a nanoparticle to have two distinguishable properties due to the different materials. Due to these pores, drug loading ability can be customized. another(prenominal) trendy nanoparticle is gold. They are used due to their special photo thermal effect one can send in light a... ...um. Nanosphere lithography is the aid best because it is used when polymers cannot be accessed. Metals are made as spheres but shapes are limited by the cry stal group chosen as the glass substrate material. Sol-gel has tons of potential but it can solely make hydrophobic materials. Microfluidization is easily the worst because it is way too pricy for such low yield. Research is being done to optimize this. entirely of these drug delivery synthesis methods can be performed fairly rapidly and are currently being used commercially, with various levels of popularity. Radical polymerisation also has the largest range of crystal properties possibilities, being able to be hydrophilic or hydrophobic. This is very unique, especially when considering it being used as a drug vehicle. Being hydrophilic can allow hydrophobic drugs to go far the body for extended amounts of time.

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